Manometry showed the abolition of reflex contraction in colonic smooth muscle. Histological examinations revealed transparent reduction and vacuolation of ganglion cells 1 week after BAC treatment with complete disappearance of ganglion cells 3 weeks after BAC treatment. 组织学检查发现BAC处理后1周结肠神经节细胞明显减少、空泡变,3周后完全消失。